Applying for a CLDF 2007 Award

Children’s Liver Disease Foundation is making available up to £80,000 for research projects in 2007. The trustees are particularly keen to receive applications for translational projects with reference to the CLDF research strategy (see link below). Collaborative projects are particularly encouraged.

Deadline for applications: 12 January 2007 (5pm)
Announcement of awards: 30 April 2007
Award start date: 1 June 2007

CLDF apologises for the short time frame for applications.

• Applications
All applications must be made using the 2007 application form which can be downloaded from this site. Applications can be made electronically.

Late applications will not be accepted.

• Review Process
Children’s Liver Disease Foundation is a member of the Association of Medical Research Charities (AMRC) and abides by their best practice guidelines and membership criteria. All applications for CLDF financial support are subject to peer review. The following process will take place:

An application is assigned to a member of the CLDF Medical Advisory Committee (MAC) by the Chairman of the CLDF MAC and CLDF Chief Executive with further guidance from the Honorary Medical Adviser. You will not normally be informed of the name of the lead internal reviewer of your application.

The lead internal reviewer and chairman of the MAC will put forward three names for the chief executive to approach to provide a review of the application, A copy of the assessor’s review form is available on this site. The chairman, lead internal reviewer and chief executive are able to seek outside advice on appropriate external reviewers.

CLDF will pass an anonymous copy of the reviewers open commentary to the applicants and invite a response, where time permits. This will be undertaken by email. CLDF will make every endeavour to contact applicants to invite a response. Responses will be tabled at the grants review meeting.

Feedback will be provided in a written format to non-successful applicants, if requested, but no further correspondence will be entered into beyond this.

• Approval of MAC recommendations for awards
Final approval of awards is made by the Board of Trustees.

• Use of animals in research
Children’s Liver Disease Foundation will make awards to projects which involve the use of animals, subject to all relevant legislation and good practice principles being adhered to by the research team. Applications involving the use of experiments in animals will be accepted provided they are accompanied by an additional questionnaire which asks for further details on the use of animals in research.

Download the CLDF 2007 Application Form - (Word document)

Download the CLDF questionnaire on the use of animals in medical research - (Word document)

Download the guidelines for applying for a CLDF grant - (PDF document)

Download the CLDF research strategy - (PDF document)

PhD studentships in inflammatory bowel disease

CICRA intends to fund a number of 3 yr PhD studentships in research groups with a proven track record of high quality output in gut immunology and inflammation or IBD genetics. The appropriate annual stipend and home/EU tuition fees will be paid as well as a modest sum for consumables. The studentships will start in Autumn 2007 for 36 months.

Application forms for supervisors containing further details of the terms and conditions of the awards are available on www.cicra.org or from:

CICRA, Parkgate House
356 West Barnes Lane,
Motspur Park,
Surrey KT3 6NB

Tel: 020 8949 6209 Fax: 020 8942 2044
E-mail: support@cicra.org

Application forms must be returned by30th November 2006

Medicines for Children Research Network

Download copy of this letter: Word PDF

Medicines for Children Research Network
Coordinating Centre
University of Liverpool
Institute of Child Health
Alder Hey Children's Hospital
Eaton Road
Liverpool
L12 2AP

www.mcrn.org.uk

Dr M Stephen Murphy
Institute of Child Health
Clinical Research Block
Whittall Street
Birmingham
B4 6NH

Tel 0121 3338705
Fax 0121 3338701
Email m.s.murphy@bham.ac.uk

7 September 2006

Dear Colleagues

MCRN Clinical Studies Group (Gastroenterology, Hepatology & Nutrition)

I wrote to you several months ago regarding this matter. It appears that not all may have received my letter, and so I thought I would contact you again. This is also an opportunity to update you on subsequent developments regarding MCRN.

You will be aware that there have been significant developments recently in relation to paediatric clinical trials in the UK. The importance of promoting trials is now receiving widespread recognition. As you know, there are a number of barriers that have tended to discourage the proper evaluation of medicines for children. The Department of Health has funded a UK Medicines for Children Research Network (MCRN) to try to counter some of these disincentives.

UK MCRN is based in Liverpool. Under that central coordination a series of six Local Research Networks (LRNs) has recently being established in England to provide support and infrastructure for clinical trials. Similar networks are developing in Scotland and Wales. Further information is available on the MCRN website (above).

MCRN established a series of Clinical Studies Groups (CSGs) covering various clinical research areas. A CSG for paediatric gastroenterology, hepatology and nutrition has been formed. The purpose of the CSG is to help in the development of a portfolio of high quality clinical trials for adoption by the MCRN. This is therefore an important opportunity for all of us.

At present our CSG consists of a core group of clinical specialists (n=7) in gastroenterology, hepatology and nutrition. Over the coming months the group will enlarge and diversify. It is intended that it will be multidisciplinary with wider expertise and interests represented.

The CSG intends to be outward looking, and welcomes the views and advice of all those with an interest in clinical trial development. We are working closely with relevant professional societies to identify and develop clinical trial proposals. We also hope to rely on colleagues from outside of the group to provide expert review and advice on trial proposals.

We have written to a wide range of individuals asking for their views, particularly in relation to the need for trials in their own particular research and clinical areas. We welcome suggestions from all who are interested, and in particular we would also value your views on priorities for trial development. It will be important in the coming months to establish such priorities, so that in collaboration with colleagues we can develop appropriate high quality trial proposals.

The CSGs are the primary portal of entry for clinical trials to be run using the resources of the MCRN. We would therefore be pleased to hear from you regarding single centre and multi-centre clinical trials that you may be considering or planning if you think it would be advantageous to run them through the network. Currently any studies adopted by the network will need to be adequately funded from a source open to national competition. The network will be able to offer expertise and administrative support. Proposals could be usefully discussed at an early phase in their development, but fully developed proposals are also welcomed. The CSG would hope to work with you towards submission of your proposal to the MCRN Trials Adoption Committee.

I am very happy to discuss the process with you if you wish.

We are fortunate to have had agreement to the establishment of a CSG dedicated to our related specialties. I hope that we will be able to take full advantage of this to gain access to the MCRN.

We will keep you informed of future developments.

With best wishes.

Yours sincerely

Dr M Stephen Murphy
Chair, CSG (Gastroenterology, Hepatology and Nutrition)

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