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Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children
Paracetamol Overdose

Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children

Joint Guideline proposed by the Children’s Specialised Liver Services at King’s, Birmingham, and Leeds.

Published: March 2024
Guidelines for the diagnosis and management of pancreatitis in children
Pancreatitis

Guidelines for the diagnosis and management of pancreatitis in children

This guideline covers the diagnosis and management of acute and chronic pancreatitis in children and young people (CYP) in the United Kingdom

Published: January 2024
Acute Liver Failure Guidelines by the The American College of Gastroenterology
Liver Failure

Acute Liver Failure Guidelines by the The American College of Gastroenterology

Acute liver failure (ALF) is a life-threatening condition that occurs in patients with no preexisting liver disease and is characterized by liver injury (abnormal liver tests), coagulopathy (international normalized ratio [INR] .1.5), and hepatic encephalopathy (HE).

Published: March 2023
Intestinal Ultrasound for the Pediatric Gastroenterologist: A Guide for Inflammatory Bowel Disease Monitoring in Children
Clinical PracticeEvidence-basedIBD

Intestinal Ultrasound for the Pediatric Gastroenterologist: A Guide for Inflammatory Bowel Disease Monitoring in Children

Expert Consensus on Behalf of the International Bowel Ultrasound Group (IBUS) Pediatric Committee.

Published: February 2023
Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition
BSGIBDLimited Scientific EvidencePosition Paper

Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition

This joint British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition guideline aims to ensure that testing resources are appropriately applied to maximise the benefit to patients on a national scale, minimise health-care disparities in accessing genomic technologies, and optimise resource use.

Published: January 2023
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review
Acute Hepatic Porphyrias

AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review

The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase.

Published: January 2023
Proposed Prolonged Jaundice Pathway following national audit 2022-2023
Jaundice

Proposed Prolonged Jaundice Pathway following national audit 2022-2023

UK Multi-center practice and adaptation of Guidelines from NICE and Liver centre conjugated hyperbilirubinemia pathway.

Published: January 2023
AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis
Clinical PracticeEvidence-basedUlcerative Colitis

AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis

Published: January 2023
ESPEN guideline on Clinical Nutrition in inflammatory bowel disease
ESPENEvidence-basedIBD

ESPEN guideline on Clinical Nutrition in inflammatory bowel disease

The guideline is aimed at professionals working in clinical practice, either in hospitals or in outpatient medicine, and treating patients with IBD. General aspects of care in patients with IBD, and specific aspects during active disease and in remission are addressed.

Published: December 2022
The management of complications associated with IgA vasculitis (Henoch Schönlein Purpura) in children and young people
Clinical PracticeEvidence-based

The management of complications associated with IgA vasculitis (Henoch Schönlein Purpura) in children and young people

UK Kidney Association Clinical Practice Guidelines for the Initial Management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people.

Published: December 2022
The initial management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people
Clinical PracticeEvidence-based

The initial management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people

A complimentary document on the best practice guidelines for the complications associated with IgAV in children and young people.

Published: December 2022
Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts
ESPGHANLimited Scientific EvidencePosition Paper

Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts

Updated ESPGHAN CoN consensus-based conclusions and recommendations on nutrient intakes and nutritional management for preterm infants.

Published: October 2022
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Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children
Paracetamol Overdose

Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children

Joint Guideline proposed by the Children’s Specialised Liver Services at King’s, Birmingham, and Leeds.

Published: March 2024
BSG Position Paper: Green Endoscopy
EndoscopyPosition PaperSustainable Health

BSG Position Paper: Green Endoscopy

Green endoscopy: British Society of Gastroenterology (BSG), Joint Accreditation Group (JAG) and Centre for Sustainable Health (CSH) joint consensus on practical measures for environmental sustainability in endoscopy.

Published: September 2022
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Management of Peutz-Jeghers Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group
ESPGHANLimited Scientific EvidencePosition Paper

Management of Peutz-Jeghers Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group

This position paper provides a guide for diagnosis, assessment, and management of PJS in children and adolescents and guidance on avoiding complications from PJS or from the endoscopic procedures performed on these patients.

Published: March 2021
Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee
ESPGHANLimited Scientific EvidencePaediatric PancreatitisPosition Paper

Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee

This position paper summarizes the current understanding of the medical management of chronic pancreatitis (CP) in children in light of the existing medical literature, incorporating recent advances in understanding of nutrition, pain, lifestyle considerations, and sequelae of CP.

Published: February 2021
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology Joint Position Paper on Noninvasive Imaging of Pediatric Pancreatitis: Literature Summary and Recommendations
Limited Scientific EvidencePaediatric PancreatitisPosition Paper

North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology Joint Position Paper on Noninvasive Imaging of Pediatric Pancreatitis: Literature Summary and Recommendations

The reported incidence of pediatric pancreatitis is increasing. Noninvasive imaging, including ultrasound computed tomography (CT), and magnetic resonance imaging (MRI), play important roles in the diagnosis, staging, follow-up, and management of pancreatitis in children.

Published: January 2021
The Medical Management of Paediatric Crohn’s Disease: an ECCO-ESPGHAN Guideline Update
Clinical PracticeEvidence-basedPaediatric Crohn’s Disease

The Medical Management of Paediatric Crohn’s Disease: an ECCO-ESPGHAN Guideline Update

We present state-of-the-art guidance on the medical treatment and long-term management of children and adolescents with CD.

Published: October 2020
ACG Clinical Guideline: Chronic Pancreatitis
ACG Clinical GuidelinesClinical PracticeEvidence-based

ACG Clinical Guideline: Chronic Pancreatitis

This guideline will provide an evidence-based practical approach to the diagnosis and management of CP for the general gastroenterologist.

Published: February 2020
BSPGHAN Motility Working Group consensus statement- Anorectal manometry in children with defecation disorders
Limited Scientific EvidenceMotilityPosition Paper

BSPGHAN Motility Working Group consensus statement- Anorectal manometry in children with defecation disorders

Guidance on the use of ARM/HRAM in children with CC and/or FI.

Published: January 2020
ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth
ACG Clinical GuidelinesClinical PracticeEvidence-based

ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth

This guideline statement evaluates criteria for diagnosis, defines the optimal methods for diagnostic testing, and summarizes treatment options for small intestinal bacterial overgrowth.

Published: January 2020
ESPGHAN New Guidelines for the Diagnosis of Paediatric Coeliac Disease
Coeliac DiseaseESPGHAN

ESPGHAN New Guidelines for the Diagnosis of Paediatric Coeliac Disease

This advice guide provides new and updated summary guidance from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) on diagnosing children and adolescents with CD.

Published: January 2020
ESPGHAN Guidelines for Diagnosing Coeliac Disease
Coeliac DiseaseESPGHAN

ESPGHAN Guidelines for Diagnosing Coeliac Disease

The ESPGHAN 2012 coeliac disease (CD) diagnostic guidelines aimed to guide physicians in accurately diagnosing CD and permit omission of duodenal biopsies in selected cases. Here, an updated and expanded evidence-based guideline is presented.

Published: January 2020
Chronic Pancreatitis and Nutrition Therapy
Review

Chronic Pancreatitis and Nutrition Therapy

Chronic pancreatitis is a complex and irreversible disease of the pancreas and is associated with significant morbidity and mortality.

Published: September 2019
Nutrition Management in Acute Pancreatitis
Review

Nutrition Management in Acute Pancreatitis

Acute pancreatitis (AP) is one of the most prevalent gastrointestinal conditions necessitating inpatient care.

Published: September 2019
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Acute Liver Failure Guidelines by the The American College of Gastroenterology
Liver Failure

Acute Liver Failure Guidelines by the The American College of Gastroenterology

Acute liver failure (ALF) is a life-threatening condition that occurs in patients with no preexisting liver disease and is characterized by liver injury (abnormal liver tests), coagulopathy (international normalized ratio [INR] .1.5), and hepatic encephalopathy (HE).

Published: March 2023
Proposed Prolonged Jaundice Pathway following national audit 2022-2023
Jaundice

Proposed Prolonged Jaundice Pathway following national audit 2022-2023

UK Multi-center practice and adaptation of Guidelines from NICE and Liver centre conjugated hyperbilirubinemia pathway.

Published: January 2023
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review
Acute Hepatic Porphyrias

AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review

The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase.

Published: January 2023
Early investigation and management of children with acute non-A-E hepatitis, with and without liver failure
Hepatitis

Early investigation and management of children with acute non-A-E hepatitis, with and without liver failure

This clinical framework is intended to provide a structure for the investigation, transfer and management of children with novel non-A-E acute hepatitis in the context of an emergence of a novel disease. The recommendations within this guidance are based on existing principles of management of acute hepatitis and acute liver failure and on expert consensus opinion in the absence of high quality evidence around this novel condition.

Published: May 2022
Assessment and Management of Oesophageal Varices in Children 
Oesophageal Varices

Assessment and Management of Oesophageal Varices in Children 

These guidelines were constructed after a joint audit and review of practice at the three specialised centres in June 2016 and reviewed again in 2021. Although evidence based where possible, where not available they represent consensus. A detailed version of this guideline which includes review of evidence, together with reference to adult evidenced based guidelines is available. Section 4: management of acute variceal bleed: is designed for implementation at any hospital to which a child presents and can be used as a stand-alone guideline.

Published: September 2021
UK Fatty Liver Guidelines
NAFLD

UK Fatty Liver Guidelines

These guidelines were constructed after a joint audit and review at the three specialised paediatric hepatology centres.

Published: August 2020
Updated shielding guidance for children with chronic liver disease and those on immunosuppression (autoimmune and liver transplantation
Chronic Liver DiseaseCOVID-19

Updated shielding guidance for children with chronic liver disease and those on immunosuppression (autoimmune and liver transplantation

In view of the continuous evidence and increasing knowledge in the COVID-19 pandemic we have undertaken an update on the advice to children and families with chronic liver disease.

Published: July 2020
NICE and ESPGHAN Guidelines
ESPGHANNICE

NICE and ESPGHAN Guidelines

These guidelines and standards have been published by NICE and ESPGHAN and are available for information. However, please do not hesitate to contact your local Paediatric Hepatology Team to discuss management of a child with any liver disorder.

Published: June 2017
Investigation of Neonatal Conjugated Jaundice
Jaundice

Investigation of Neonatal Conjugated Jaundice

This guideline aims to advise clinicians on the initial investigations necessary when an infant with conjugated jaundice is identified.

Published: December 2016
Investigation and treatment of liver disease with acute onset
Liver Disease

Investigation and treatment of liver disease with acute onset

 Defined as EITHER sudden onset of jaundice with evidence of liver aetiology OR incidental discovery of raised transaminases in association with symptoms suggesting acute onset.

Published: July 2013
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ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Standard versus individualized parenteral nutrition
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Standard versus individualized parenteral nutrition

PN can be provided as a standard, usually commercial, formulation that is designed to meet the nutritional needs of most patients of the same age group with a similar condition.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Lipids
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Lipids

The rate, amount, and type of lipids provided intravenously are important aspects regarding the efficacy and safety in neonates and children.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Iron and trace minerals
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Iron and trace minerals

Iron is an essential nutrient and iron deficiency results in anemia as well as poor neurodevelopment in children.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Fluid and electrolytes
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Fluid and electrolytes

The aim of the current revision is to update the previous chapter on basis of the scientific evidence published since 2004.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Energy
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Energy

Energy supply needs to meet the nutritional needs of the patient which include basal metabolic rate, physical activity, growth, diet induced thermogenesis and correction of pre-existing malnutrition.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Carbohydrates
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Carbohydrates

Carbohydrates are the main source of energy in nutrition and usually provide 40-60% of the energy supply in western diets.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Calcium, phosphorus and magnesium
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Calcium, phosphorus and magnesium

In infants and children growth is the major determinant of mineral requirements.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Amino acids
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Amino acids

Recommendations were developed from a standpoint of nutrient adequacy. Depending on age groups, nutrient adequacy was based on intrauterine accretion rate, organ development, factorial estimates of requirements and amino acid interactions. Individual amino acids are discussed.

Published: May 2018
Recommendations for Nutritional Management of Children with Neurological Impairment (NI)
ESPGHANLimited Scientific EvidencePosition Paper

Recommendations for Nutritional Management of Children with Neurological Impairment (NI)

This guide provides recommendations and a systematic approach for the care of paediatric patients with NI.

Published: August 2017

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