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Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children
Paracetamol Overdose

Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children

Joint Guideline proposed by the Children’s Specialised Liver Services at King’s, Birmingham, and Leeds.

Published: March 2024
Guidelines for the diagnosis and management of pancreatitis in children
Pancreatitis

Guidelines for the diagnosis and management of pancreatitis in children

This guideline covers the diagnosis and management of acute and chronic pancreatitis in children and young people (CYP) in the United Kingdom

Published: January 2024
Acute Liver Failure Guidelines by the The American College of Gastroenterology
Liver Failure

Acute Liver Failure Guidelines by the The American College of Gastroenterology

Acute liver failure (ALF) is a life-threatening condition that occurs in patients with no preexisting liver disease and is characterized by liver injury (abnormal liver tests), coagulopathy (international normalized ratio [INR] .1.5), and hepatic encephalopathy (HE).

Published: March 2023
Intestinal Ultrasound for the Pediatric Gastroenterologist: A Guide for Inflammatory Bowel Disease Monitoring in Children
Clinical PracticeEvidence-basedIBD

Intestinal Ultrasound for the Pediatric Gastroenterologist: A Guide for Inflammatory Bowel Disease Monitoring in Children

Expert Consensus on Behalf of the International Bowel Ultrasound Group (IBUS) Pediatric Committee.

Published: February 2023
Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition
BSGIBDLimited Scientific EvidencePosition Paper

Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition

This joint British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition guideline aims to ensure that testing resources are appropriately applied to maximise the benefit to patients on a national scale, minimise health-care disparities in accessing genomic technologies, and optimise resource use.

Published: January 2023
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review
Acute Hepatic Porphyrias

AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review

The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase.

Published: January 2023
Proposed Prolonged Jaundice Pathway following national audit 2022-2023
Jaundice

Proposed Prolonged Jaundice Pathway following national audit 2022-2023

UK Multi-center practice and adaptation of Guidelines from NICE and Liver centre conjugated hyperbilirubinemia pathway.

Published: January 2023
AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis
Clinical PracticeEvidence-basedUlcerative Colitis

AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis

Published: January 2023
ESPEN guideline on Clinical Nutrition in inflammatory bowel disease
ESPENEvidence-basedIBD

ESPEN guideline on Clinical Nutrition in inflammatory bowel disease

The guideline is aimed at professionals working in clinical practice, either in hospitals or in outpatient medicine, and treating patients with IBD. General aspects of care in patients with IBD, and specific aspects during active disease and in remission are addressed.

Published: December 2022
The management of complications associated with IgA vasculitis (Henoch Schönlein Purpura) in children and young people
Clinical PracticeEvidence-based

The management of complications associated with IgA vasculitis (Henoch Schönlein Purpura) in children and young people

UK Kidney Association Clinical Practice Guidelines for the Initial Management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people.

Published: December 2022
The initial management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people
Clinical PracticeEvidence-based

The initial management of IgA vasculitis (Henoch Schönlein Purpura) in children and young people

A complimentary document on the best practice guidelines for the complications associated with IgAV in children and young people.

Published: December 2022
Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts
ESPGHANLimited Scientific EvidencePosition Paper

Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts

Updated ESPGHAN CoN consensus-based conclusions and recommendations on nutrient intakes and nutritional management for preterm infants.

Published: October 2022
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Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children
Paracetamol Overdose

Assessment, monitoring and management of deliberate and accidental paracetamol overdose in Children

Joint Guideline proposed by the Children’s Specialised Liver Services at King’s, Birmingham, and Leeds.

Published: March 2024
BSG Position Paper: Green Endoscopy
EndoscopyPosition PaperSustainable Health

BSG Position Paper: Green Endoscopy

Green endoscopy: British Society of Gastroenterology (BSG), Joint Accreditation Group (JAG) and Centre for Sustainable Health (CSH) joint consensus on practical measures for environmental sustainability in endoscopy.

Published: September 2022
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Management of Exocrine Pancreatic Insufficiency in Children
Review

Management of Exocrine Pancreatic Insufficiency in Children

The diagnosis of exocrine pancreatic insufficiency (EPI) can be difficult, as symptoms may be nonspecific.

Published: September 2019
Practical guide to the management of acute pancreatitis
Acute PancreatitisLimited Scientific EvidencePosition Paper

Practical guide to the management of acute pancreatitis

Position paper discussing current diagnostic and management challenges and addressing the common dilemmas in AP.

Published: March 2019
2019 WSES guidelines for the management of severe acute pancreatitis
Acute PancreatitisLimited Scientific EvidencePosition Paper

2019 WSES guidelines for the management of severe acute pancreatitis

The main topics of these guidelines fall under the following topics: Diagnosis, Antibiotic treatment, Management in the Intensive Care Unit, Surgical and operative management, and Open abdomen.

Published: January 2019
Part 1: Ambulatory Care – An Evidence-based Guideline From European Crohn’s and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition
Limited Scientific EvidencePaediatric Ulcerative ColitisPosition Paper

Part 1: Ambulatory Care – An Evidence-based Guideline From European Crohn’s and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition

These guidelines provide a guide to clinicians managing children with UC and IBD-unclassified management to provide modern management strategies while maintaining vigilance around appropriate outcomes and safety issues.

Published: August 2018
Part 2: Acute Severe Colitis – An Evidence-based Consensus Guideline From the European Crohn’s and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition
Limited Scientific EvidencePaediatric Ulcerative ColitisPosition Paper

Part 2: Acute Severe Colitis – An Evidence-based Consensus Guideline From the European Crohn’s and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition

These guidelines standardize the management of ASC in children in an attempt to optimize outcomes of this intensive clinical scenario.

Published: August 2018
Paediatric Intestinal Pseudo-obstruction: Evidence and Consensus-based Recommendations From an ESPGHAN-Led Expert Group
ESPGHANLimited Scientific EvidencePosition Paper

Paediatric Intestinal Pseudo-obstruction: Evidence and Consensus-based Recommendations From an ESPGHAN-Led Expert Group

This document is intended to be used in daily practice from the time of first presentation and definitive diagnosis PIPO through to the complex management and treatment interventions such as intestinal transplantation.

Published: June 2018
GI Bleeding Pathway
Endoscopy

GI Bleeding Pathway

GI Bleeding pathway details. Pathway to be read in conjunction with Assessment and Management of Oesophageal Varices in Children

Published: March 2018
Joint NASPGHAN and ESPGHAN guidelines on Gastro-oesophageal Reflux Disease in Children
Clinical PracticeEvidence-basedGastro-oesophageal Reflux Disease

Joint NASPGHAN and ESPGHAN guidelines on Gastro-oesophageal Reflux Disease in Children

This document serves as an update of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) 2009 clinical guidelines for the diagnosis and management of gastroesophageal reflux disease (GERD) in infants and children and is intended to be applied in daily practice and as a basis for clinical trials.

Published: March 2018
American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis
Acute PancreatitisLimited Scientific EvidencePosition Paper

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

This document presents the official recommendations of the American Gastroenterological Association (AGA) on the initial management of acute pancreatitis (AP).

Published: January 2018
Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents
Clinical PracticeEvidence-basedHelicobacter Pylori

Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents

The primary goal of clinical investigation is to identify the cause of upper gastrointestinal symptoms rather than H pylori infection. Therefore, we recommend against a test and treat strategy.

Published: June 2017
BSPGHAN Motility Working Group position statement: paediatric multichannel intraluminal pH impedance monitoring—indications, methods and interpretation
Limited Scientific EvidenceMotilityPosition Paper

BSPGHAN Motility Working Group position statement: paediatric multichannel intraluminal pH impedance monitoring—indications, methods and interpretation

MII-pH is increasingly used by paediatricians as the diagnostic tool for assessing gastro-oesophageal reflux disease and symptom association. There is wide variation in paediatric practice and a need for standardised practice.

Published: March 2017
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Acute Liver Failure Guidelines by the The American College of Gastroenterology
Liver Failure

Acute Liver Failure Guidelines by the The American College of Gastroenterology

Acute liver failure (ALF) is a life-threatening condition that occurs in patients with no preexisting liver disease and is characterized by liver injury (abnormal liver tests), coagulopathy (international normalized ratio [INR] .1.5), and hepatic encephalopathy (HE).

Published: March 2023
Proposed Prolonged Jaundice Pathway following national audit 2022-2023
Jaundice

Proposed Prolonged Jaundice Pathway following national audit 2022-2023

UK Multi-center practice and adaptation of Guidelines from NICE and Liver centre conjugated hyperbilirubinemia pathway.

Published: January 2023
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review
Acute Hepatic Porphyrias

AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review

The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase.

Published: January 2023
Early investigation and management of children with acute non-A-E hepatitis, with and without liver failure
Hepatitis

Early investigation and management of children with acute non-A-E hepatitis, with and without liver failure

This clinical framework is intended to provide a structure for the investigation, transfer and management of children with novel non-A-E acute hepatitis in the context of an emergence of a novel disease. The recommendations within this guidance are based on existing principles of management of acute hepatitis and acute liver failure and on expert consensus opinion in the absence of high quality evidence around this novel condition.

Published: May 2022
Assessment and Management of Oesophageal Varices in Children 
Oesophageal Varices

Assessment and Management of Oesophageal Varices in Children 

These guidelines were constructed after a joint audit and review of practice at the three specialised centres in June 2016 and reviewed again in 2021. Although evidence based where possible, where not available they represent consensus. A detailed version of this guideline which includes review of evidence, together with reference to adult evidenced based guidelines is available. Section 4: management of acute variceal bleed: is designed for implementation at any hospital to which a child presents and can be used as a stand-alone guideline.

Published: September 2021
UK Fatty Liver Guidelines
NAFLD

UK Fatty Liver Guidelines

These guidelines were constructed after a joint audit and review at the three specialised paediatric hepatology centres.

Published: August 2020
Updated shielding guidance for children with chronic liver disease and those on immunosuppression (autoimmune and liver transplantation
Chronic Liver DiseaseCOVID-19

Updated shielding guidance for children with chronic liver disease and those on immunosuppression (autoimmune and liver transplantation

In view of the continuous evidence and increasing knowledge in the COVID-19 pandemic we have undertaken an update on the advice to children and families with chronic liver disease.

Published: July 2020
NICE and ESPGHAN Guidelines
ESPGHANNICE

NICE and ESPGHAN Guidelines

These guidelines and standards have been published by NICE and ESPGHAN and are available for information. However, please do not hesitate to contact your local Paediatric Hepatology Team to discuss management of a child with any liver disorder.

Published: June 2017
Investigation of Neonatal Conjugated Jaundice
Jaundice

Investigation of Neonatal Conjugated Jaundice

This guideline aims to advise clinicians on the initial investigations necessary when an infant with conjugated jaundice is identified.

Published: December 2016
Investigation and treatment of liver disease with acute onset
Liver Disease

Investigation and treatment of liver disease with acute onset

 Defined as EITHER sudden onset of jaundice with evidence of liver aetiology OR incidental discovery of raised transaminases in association with symptoms suggesting acute onset.

Published: July 2013
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ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Standard versus individualized parenteral nutrition
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Standard versus individualized parenteral nutrition

PN can be provided as a standard, usually commercial, formulation that is designed to meet the nutritional needs of most patients of the same age group with a similar condition.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Lipids
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Lipids

The rate, amount, and type of lipids provided intravenously are important aspects regarding the efficacy and safety in neonates and children.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Iron and trace minerals
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Iron and trace minerals

Iron is an essential nutrient and iron deficiency results in anemia as well as poor neurodevelopment in children.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Fluid and electrolytes
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Fluid and electrolytes

The aim of the current revision is to update the previous chapter on basis of the scientific evidence published since 2004.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Energy
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Energy

Energy supply needs to meet the nutritional needs of the patient which include basal metabolic rate, physical activity, growth, diet induced thermogenesis and correction of pre-existing malnutrition.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Carbohydrates
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Carbohydrates

Carbohydrates are the main source of energy in nutrition and usually provide 40-60% of the energy supply in western diets.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Calcium, phosphorus and magnesium
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Calcium, phosphorus and magnesium

In infants and children growth is the major determinant of mineral requirements.

Published: May 2018
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Amino acids
CSPENESPENESPGHANESPREvidence-based

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Amino acids

Recommendations were developed from a standpoint of nutrient adequacy. Depending on age groups, nutrient adequacy was based on intrauterine accretion rate, organ development, factorial estimates of requirements and amino acid interactions. Individual amino acids are discussed.

Published: May 2018
Recommendations for Nutritional Management of Children with Neurological Impairment (NI)
ESPGHANLimited Scientific EvidencePosition Paper

Recommendations for Nutritional Management of Children with Neurological Impairment (NI)

This guide provides recommendations and a systematic approach for the care of paediatric patients with NI.

Published: August 2017

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